Similar to insulin in its molecular properties, IGF-1 is a polypeptide hormone and stands for insulin-like growth factor. IGF-1 LR3 is the primary protein when it comes to the responses of cells to growth hormone (also known as GH).
Benefits of IGF-1LR3
In our bodies, IGF-I is produced as a direct response to growth hormone and subsequently motivates cellular activities. An example of these cellular activities is hyperplasia (or musclegrowth). IGF-1 has been pinpointed as causing muscle cell hyperplasia (the splitting and forming of new muscle cells). This particular compound also makes the human tissue more sensitive to insulin.
Amongst its different forms IGF1 and IGF1-DES, IGF-1 LR3 is considered to be the most effective since the formula has been altered chemically to avoid the possibility of attaching itself to proteins in the human body. Its chemical reformulation also increases its half-life, bringing it up to 30 hours.
This IGF-1 analogue has been developed to increase and improve the biological activity of the peptide. The benefits of this format of IGF-1 are the following;
• Increased amino acid transported to cells
• Increased protein sysynthesis
• Decrease protein deterioration
• Elevate glucose transport
It has been noted that IGF behaves differently based on what kind of tissue it is active in. When in muscle cells protein, and its associated cell components, is stimulated. It will also increase protein synthesis and amino acid absorption.
Finally, IGF acts as an energy source as it mobilizes fat in adipose tissue to be used as energy. When active in muscle tissue, IGF-1 LR3 stops insulin from taking glucose through cell membranes. This forces cells to burn fat as it’s prime energy source instead of glucose giving visibly lower body fat in a short period of time.
IGF-1 LR3 also works in building new muscle tissue since it actively promotes protein synthesis and nitrogen retention which causes the growth of muscle through hyperplasia and mitogenesis (new muscle fibre growth) INCREASING the number of muscle fibres. So what does this mean? IGF-1 LR3 results in the growth muscle size as well as quantity of new muscle fibres.
IGF-1 LR3 can be taken seven days a week in doses that range between 20-120 mg per day with the average dosage used being 100 Mg.
Desensitization for cell receptor’s is common after 30 to 40 days of use and is recommended to stop using this peptide for 2 weeks before starting again.
Any muscle group in the body is suitable for injection of this peptide. Recommended time for administration of injection is during the morning or pre /post work out. Half-life of IGF-1LR3 is 24 - 30 hours.
It is note worthy that high doses of IGF-1 have caused hypoglycaemia. A well structured daily diet is recommended while using this peptide.