Selank is a synthetic derivative of the human body’s naturally produced tetrapeptide Tuftsin. It is a hexapeptide with a wide range of effective uses. It was first synthesized in the late 1990’s by the Institute of Molecular Genetics of the Russian Academy of Science.

Selank is used as an anxiolytics in the therapy of anxiety and phobic disorders, including generalised anxiety and depression. Its action is similar to that of mild benzodiazepins but without the sedative effects. As a selective anxiolytic with a nootropic component, Selank can be used as treatment of chronic depression, fears, phobias and general anxiety, also reduceing phsychic tension. This neuropeptide has passed all phases of clinical trials and is now being prepared for registration and mass production.

Selank is closely related to Semax, a hexapeptide previously invented by the same institute. Some consider Selank to be a more efficient alternative to Semax – a drug currently approved for use in Russia and Ukraine.

Recreationally Selank is used to improve one’s ability to focus and concentrate, reduce mental fatigue, increase mental sharpness and increase memory and learning capacity. The first noticeable effect is usually stabilization of mood and general feeling of well-being.

Selank neuropeptide also expresses immunomodulatory effects. A study in 2009 evaluated antiviral properties of Selank both in vitro and in vivo against the influenza virus's train A/Aichi 2/68 (H3N2). The pronounced antiviral effect of Selank was detected in both systems. The highest efficiency – completely supressed viral reproduction was shown when Selank was added to the cell culture 24 hours before inoculation.

Selank effects

Experimental and clinical studies showed the following pharmaclogical effects of Selank:

·        improvement of learning and memory processes

·        increased sensory attention

·        increased mental clarity

·        restoration of balance of serotonergic and noradrenergic brain system activity

·        anti-anxiety – inhibition of anxiety

·        antiviral activity with no negative effects

·        psychostimulant, anti-asthenic – increased mental energy

·        stabilization of mood and overall feeling of wellbeing

·        reversal of anhedonia (restoring the feeling of pleasure)

·        potential restoration of catecholaminergic system functions after damage due to drug abuse

.        increased curiosity

Dosage

It’s always best to start with a low dose and gradually build up to your individual comfortable levels.

Research has shown that intranasal (nasal spray) delivery of Selank is roughly 9 times more effective than injectable. This is attributed to some of it being able to bypass the blood-brain barrier.

1. Selankas nasal spray (more effective):

·        duration: from 10 days to as long as needed

·        dosage: between 400 mg – 9 mg of Selank per day

·        daily frequency - total daily dosage split into 3 doses throughout the day.

2. InjectableSelank use:

·        duration: from 10 days to as long as needed

·        dosage: between 250 mg – 3 mg per day

·        frequency of injection: 1 injection per day for low dose, 2 injections for higher dose (divided between morning and late afternoon injection).